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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKD
All Species:
20.61
Human Site:
S974
Identified Species:
45.33
UniProt:
Q16760
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16760
NP_003639.2
1214
134525
S974
S
L
H
P
E
M
L
S
E
E
E
A
T
Q
M
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
A981
T
H
L
Y
I
H
H
A
I
D
L
A
T
E
E
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
S927
S
L
H
P
E
M
L
S
E
E
E
A
T
Q
M
Dog
Lupus familis
XP_543293
1324
146248
S1084
S
L
H
P
E
I
L
S
E
E
E
A
T
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
NP_808314
1220
135190
S976
S
L
H
P
E
I
L
S
E
E
E
A
T
Q
M
Rat
Rattus norvegicus
XP_347259
1196
133109
S956
S
L
H
P
E
I
L
S
E
E
E
A
T
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
A1014
P
H
L
Y
P
Q
Q
A
V
D
L
A
T
E
E
Chicken
Gallus gallus
XP_001232791
1333
149344
A1093
S
P
L
Y
P
Q
Q
A
V
E
L
A
T
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693512
1148
127826
A911
P
V
Q
V
D
G
E
A
W
I
Q
P
P
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
S1657
N
S
T
D
E
V
I
S
E
R
E
C
Y
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
R907
N
E
E
I
E
V
V
R
H
F
C
G
T
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.2
93.4
85.1
N.A.
93.7
90.2
N.A.
66.9
63.9
N.A.
60.9
N.A.
34.8
N.A.
N.A.
53.3
Protein Similarity:
100
76.3
94.1
87.8
N.A.
96.4
93.3
N.A.
77.4
73.8
N.A.
71.6
N.A.
46.5
N.A.
N.A.
65.8
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
13.3
26.6
N.A.
0
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
33.3
40
N.A.
33.3
N.A.
53.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
37
0
0
0
73
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
0
10
10
0
64
0
10
0
55
55
55
0
0
28
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% G
% His:
0
19
46
0
0
10
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
28
10
0
10
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
46
28
0
0
0
46
0
0
0
28
0
0
0
10
% L
% Met:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
46
% M
% Asn:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
10
0
46
19
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
0
10
0
0
19
19
0
0
0
10
0
0
46
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
55
10
0
0
0
0
0
55
0
0
0
0
0
0
10
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
0
0
82
10
0
% T
% Val:
0
10
0
10
0
19
10
0
19
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
28
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _